| Product Name | Troponin I-C |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNNI3 antibody; TNNC1 antibody; Troponin I antibody; cardiac muscle antibody; Cardiac troponin I antibody; |
| Product description | Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). |
| Immunogen | The antiserum was produced against synthesized peptide derived from mouse TNNI3. AA range:5-54 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | MouseRat |
| Concentration | 1mg/ml |
| Alternative Names | TNNI3 antibody TNNC1 antibody Troponin I antibody cardiac muscle antibody Cardiac troponin I antibody |
|---|---|
| Molecular Weight(MW) | 28 kDa |
| SwissProt ID | P48787 |
|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
