| Product Name | TRβ1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | THRB antibody; ERBA2 antibody; NR1A2 antibody; THR1 antibody; Thyroid hormone receptor beta antibody; Nuclear receptor subfamily 1 group A member 2 antibody; c-erbA-2 antibody; c-erbA-beta antibody; |
| Product description | The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Thyroid Hormone Receptor beta. AA range:11-60 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | THRB antibody ERBA2 antibody NR1A2 antibody THR1 antibody Thyroid hormone receptor beta antibody Nuclear receptor subfamily 1 group A member 2 antibody c-erbA-2 antibody c-erbA-beta antibody |
|---|---|
| Molecular Weight(MW) | 53 kDa |
| SwissProt ID | P10828 |
|---|
| Positive Control | Brain,Kidney,Pituitary,Placenta,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
