| Product Name | TTK |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TTK antibody; MPS1 antibody; MPS1L1 antibody; Dual specificity protein kinase TTK antibody; Phosphotyrosine picked threonine-protein kinase antibody; PYT antibody; |
| Product description | This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TTK. AA range:642-691 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | TTK antibody MPS1 antibody MPS1L1 antibody Dual specificity protein kinase TTK antibody Phosphotyrosine picked threonine-protein kinase antibody PYT antibody |
|---|---|
| Molecular Weight(MW) | 100 kDa |
| SwissProt ID | P33981 |
|---|
| Positive Control | Epithelium,Eye,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
