| Product Name | TWEAK |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNFSF12 antibody; APO3L antibody; DR3LG antibody; Tumor necrosis factor ligand superfamily member 12 antibody; APO3 ligand antibody; TNF-related weak inducer of apoptosis antibody; TWEAK antibody; |
| Product description | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TNFSF12. AA range:41-90 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | TNFSF12 antibody APO3L antibody DR3LG antibody Tumor necrosis factor ligand superfamily member 12 antibody APO3 ligand antibody TNF-related weak inducer of apoptosis antibody TWEAK antibody |
|---|---|
| Molecular Weight(MW) | 27 kDa |
| SwissProt ID | O43508 |
|---|
| Positive Control | Cerebellum,Fetal kidney,Fetal liver,Ovary,PCR rescued clone |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
