| Product Name |
UBE3C |
| Antibody Type |
Primary Antibodies |
| Antigen Alias |
UBE3C antibody; KIAA0010 antibody; KIAA10 antibody; Ubiquitin-protein ligase E3C antibody; HectH2 antibody; |
| Product description |
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo. miscellaneous:A cysteine residue is required for ubiquitin-thioester formation. pathway:Protein modification; protein ubiquitination. Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain. Contains 1 IQ domain. subunit:Interacts with 26S proteasomes. Binds CAND2. tissue specificity:Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas. |
| Immunogen |
Synthesized peptide derived from the Internal region of human UBE3C. |
