| Product Name | Ubr1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | UBR1 antibody; E3 ubiquitin-protein ligase UBR1 antibody; N-recognin-1 antibody; Ubiquitin-protein ligase E3-alpha-1 antibody; Ubiquitin-protein ligase E3-alpha-I antibody; |
| Product description | The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human UBR1. AA range:821-870 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | UBR1 antibody E3 ubiquitin-protein ligase UBR1 antibody N-recognin-1 antibody Ubiquitin-protein ligase E3-alpha-1 antibody Ubiquitin-protein ligase E3-alpha-I antibody |
|---|---|
| Molecular Weight(MW) | 36 kDa |
| SwissProt ID | Q8IWV7 |
|---|
| Positive Control | Brain,Epithelium,Erythroid cell,Heart,Placenta, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
