catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol. Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. sequence caution:Translation N-terminally shortened. Belongs to the peptidase C19 family. Contains 1 MYND-type zinc finger. Contains 2 CS domains.
Immunogen
The antiserum was produced against synthesized peptide derived from human USP19. AA range:391-440