| Product Name | VPS72 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | VPS72 antibody; TCFL1 antibody; YL1 antibody; Vacuolar protein sorting-associated protein 72 homolog antibody; Protein YL-1 antibody; Transcription factor-like 1 antibody; |
| Product description | The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human VPS72. AA range:131-180 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | VPS72 antibody TCFL1 antibody YL1 antibody Vacuolar protein sorting-associated protein 72 homolog antibody Protein YL-1 antibody Transcription factor-like 1 antibody |
|---|---|
| Molecular Weight(MW) | 41 kDa |
| SwissProt ID | Q15906 |
|---|
| Positive Control | Fibroblast,Kidney, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
