| Product Name | XIAP |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | XIAP antibody; API3 antibody; BIRC4 antibody; IAP3 antibody; E3 ubiquitin-protein ligase XIAP antibody; Baculoviral IAP repeat-containing protein 4 antibody; IAP-like protein antibody; ILP antibody; hILP antibody; Inhibitor of apoptosis protein 3 antibody; IAP-3 antibody; hIAP-3 antibody; hIAP3 antibody; X-linked inhibitor of apoptosis protein antibody; X-linked I antibody; |
| Product description | This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11., |
| Immunogen | The antiserum was produced against synthesized peptide derived from human XIAP. AA range:53-102 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | XIAP antibody API3 antibody BIRC4 antibody IAP3 antibody E3 ubiquitin-protein ligase XIAP antibody Baculoviral IAP repeat-containing protein 4 antibody IAP-like protein antibody ILP antibody hILP antibody Inhibitor of apoptosis protein 3 antibody IAP-3 antibody hIAP-3 antibody hIAP3 antibody X-linked inhibitor of apoptosis protein antibody X-linked I antibody |
|---|---|
| Molecular Weight(MW) | 57 kDa |
| SwissProt ID | P98170 |
|---|
| Positive Control | Fetal brain,Fetal heart,Uterus, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
