| Product Name | SLP-76 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LCP2 antibody; Lymphocyte cytosolic protein 2 antibody; SH2 domain-containing leukocyte protein of 76 kDa antibody; SLP-76 tyrosine phosphoprotein antibody; SLP76 antibody; |
| Product description | SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T c |
| Immunogen | Synthesized peptide derived from SLP-76 . at AA range: 270-350 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | LCP2 antibody Lymphocyte cytosolic protein 2 antibody SH2 domain-containing leukocyte protein of 76 kDa antibody SLP-76 tyrosine phosphoprotein antibody SLP76 antibody |
|---|---|
| Molecular Weight(MW) | 60 kDa |
| SwissProt ID | Q13094 |
|---|
| Positive Control | Leukemia,Platelet,Prostate,T-cell, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
