UBE4A antibody; KIAA0126 antibody; Ubiquitin conjugation factor E4 A antibody;
Product description
This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen
Synthesized peptide derived from the N-terminal region of human UBE4A.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIHC
WB:1:500-1:2000 IHC:1:100-300
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
UBE4A antibody KIAA0126 antibody Ubiquitin conjugation factor E4 A antibody