| Product Name | NF-L |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NEFL antibody; NF68 antibody; NFL antibody; Neurofilament light polypeptide antibody; NF-L antibody; 68 kDa neurofilament protein antibody; Neurofilament triplet L protein antibody; |
| Product description | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. |
| Immunogen | Synthesized peptide derived from the C-terminal region of human NF-L. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | NEFL antibody NF68 antibody NFL antibody Neurofilament light polypeptide antibody NF-L antibody 68 kDa neurofilament protein antibody Neurofilament triplet L protein antibody |
|---|---|
| Molecular Weight(MW) | 61 kDa |
| SwissProt ID | P07196 |
|---|
| Positive Control | Amygdala,Brain,Fetal brain cortex,Thalamus, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
