| Product Name | NCX1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SLC8A1 antibody; CNC antibody; NCX1 antibody; Sodium/calcium exchanger 1 antibody; Na(+)/Ca(2+)-exchange protein 1 antibody; |
| Product description | In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation., |
| Immunogen | Synthesized peptide derived from NCX1 . at AA range: 270-350 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | SLC8A1 antibody CNC antibody NCX1 antibody Sodium/calcium exchanger 1 antibody Na(+)/Ca(2+)-exchange protein 1 antibody |
|---|---|
| Molecular Weight(MW) | 108 kDa |
| SwissProt ID | P32418 |
|---|
| Positive Control | Airway smooth muscle,Brain,Heart,Liver,PCR rescued clones,Placenta, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
