| Product Name | DR3 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNFRSF25 antibody; APO3 antibody; DDR3 antibody; DR3 antibody; TNFRSF12 antibody; WSL antibody; WSL1 antibody; Tumor necrosis factor receptor superfamily member 25 antibody; Apo-3 antibody; Apoptosis-inducing receptor AIR antibody;Apoptosis-mediating receptor DR3 antibody; Apoptosis-mediating receptor TRAMP antibody; Death receptor 3 antibody; Lymphocyte-associated receptor of death antibody; LARD antibody; Protein WSL antibody; Protein WSL-1 antibody; |
| Product description | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involve |
| Immunogen | Synthesized peptide derived from DR3 . at AA range: 230-310 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | TNFRSF25 antibody APO3 antibody DDR3 antibody DR3 antibody TNFRSF12 antibody WSL antibody WSL1 antibody Tumor necrosis factor receptor superfamily member 25 antibody Apo-3 antibody Apoptosis-inducing receptor AIR antibody Apoptosis-mediating receptor DR3 antibody Apoptosis-mediating receptor TRAMP antibody Death receptor 3 antibody Lymphocyte-associated receptor of death antibody LARD antibody Protein WSL antibody Protein WSL-1 antibody |
|---|---|
| Molecular Weight(MW) | 45 kDa |
| SwissProt ID | Q93038 |
|---|
| Positive Control | Brain,Fetal lung,Heart,Lymphoid,Umbilical vein endothelial cell, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
