| Product Name | CPE |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CPE antibody; Carboxypeptidase E antibody; CPE antibody; Carboxypeptidase H antibody; CPH antibody; Enkephalin convertase antibody; Prohormone-processing carboxypeptidase antibody; |
| Product description | This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes. |
| Immunogen | The antiserum was produced against synthesized peptide derived from the C-terminal region of human CPE. AA range:427-476 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | CPE antibody Carboxypeptidase E antibody CPE antibody Carboxypeptidase H antibody CPH antibody Enkephalin convertase antibody Prohormone-processing carboxypeptidase antibody |
|---|---|
| Molecular Weight(MW) | 53 kDa |
| SwissProt ID | P16870 |
|---|
| Positive Control | Brain,Colon,Eye, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
