| Product Name | DPYD |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DPYD antibody; Dihydropyrimidine dehydrogenase [NADP(+)] antibody; DHPDHase antibody; DPD antibody; Dihydrothymine dehydrogenase antibody; Dihydrouracil dehydrogenase antibody; |
| Product description | The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human DPYD. AA range:351-400 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | DPYD antibody Dihydropyrimidine dehydrogenase [NADP(+)] antibody DHPDHase antibody DPD antibody Dihydrothymine dehydrogenase antibody Dihydrouracil dehydrogenase antibody |
|---|---|
| Molecular Weight(MW) | 120 kDa |
| SwissProt ID | Q12882 |
|---|
| Positive Control | Liver,Skin,Uterus, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
