| Product Name | VHR |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DUSP3 antibody; VHR antibody; Dual specificity protein phosphatase 3 antibody; Dual specificity protein phosphatase VHR antibody; Vaccinia H1-related phosphatase antibody; VHR antibody; |
| Product description | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast ca |
| Immunogen | The antiserum was produced against synthesized peptide derived from the C-terminal region of human DUSP3. AA range:136-185 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | DUSP3 antibody VHR antibody Dual specificity protein phosphatase 3 antibody Dual specificity protein phosphatase VHR antibody Vaccinia H1-related phosphatase antibody VHR antibody |
|---|---|
| Molecular Weight(MW) | 21 kDa |
| SwissProt ID | P51452 |
|---|
| Positive Control | Duodenum,Uterus, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
