| Product Name | SPTLC1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SPTLC1 antibody; LCB1 antibody; Serine palmitoyltransferase 1 antibody; Long chain base biosynthesis protein 1 antibody; LCB 1 antibody; Serine-palmitoyl-CoA transferase 1 antibody; SPT 1 antibody; SPT1 antibody; |
| Product description | This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. |
| Immunogen | Synthesized peptide derived from SPTLC1 . at AA range: 411-460 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | SPTLC1 antibody LCB1 antibody Serine palmitoyltransferase 1 antibody Long chain base biosynthesis protein 1 antibody LCB 1 antibody Serine-palmitoyl-CoA transferase 1 antibody SPT 1 antibody SPT1 antibody |
|---|---|
| Molecular Weight(MW) | 52 kDa |
| SwissProt ID | O15269 |
|---|
| Positive Control | Brain,Kidney, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
