| Product Name | Integrin α4 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ITGA4 antibody; CD49D antibody; Integrin alpha-4 antibody; CD49 antigen-like family member D antibody; Integrin alpha-IV antibody; VLA-4 subunit alpha antibody; CD49d antibody; |
| Product description | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human ITGA4. AA range:571-620 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | ITGA4 antibody CD49D antibody Integrin alpha-4 antibody CD49 antigen-like family member D antibody Integrin alpha-IV antibody VLA-4 subunit alpha antibody CD49d antibody |
|---|---|
| Molecular Weight(MW) | 120 kDa |
| SwissProt ID | P13612 |
|---|
| Positive Control | Lymph,Peripheral blood,Prostate,Spleen,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
