| Product Name | Siglec-5/14 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SIGLEC5 antibody; CD33L2 antibody; OBBP2 antibody; Sialic acid-binding Ig-like lectin 5 antibody; Siglec-5 antibody; CD33 antigen-like 2 antibody; Obesity-binding protein 2 antibody; OB-BP2 antibody; OB-binding protein 2 antibody; CD170 antibody; SIGLEC14 antibody; Sialic acid-binding Ig-like lectin 14 antibody; Siglec-14 antibody; |
| Product description | This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. |
| Immunogen | Synthesized peptide derived from Sialic acid-binding Ig-like lectin 5/Sialic acid-binding Ig-like lectin 14 at AA range: 91-140 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SIGLEC5 antibody CD33L2 antibody OBBP2 antibody Sialic acid-binding Ig-like lectin 5 antibody Siglec-5 antibody CD33 antigen-like 2 antibody Obesity-binding protein 2 antibody OB-BP2 antibody OB-binding protein 2 antibody CD170 antibody SIGLEC14 antibody Sialic acid-binding Ig-like lectin 14 antibody Siglec-14 antibody |
|---|---|
| Molecular Weight(MW) | 60 kDa |
| SwissProt ID | O15389 |
|---|
| Positive Control | Brain,Erythroleukemia,Macrophage, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
