| Product Name | CD158z |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KIR3DL3 antibody; CD158Z antibody; KIR3DL7 antibody; KIRC1 antibody; Killer cell immunoglobulin-like receptor 3DL3 antibody; CD158 antigen-like family member Z antibody; Killer cell inhibitory receptor 1 antibody; CD158z antibody; |
| Product description | Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13. 4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human KIR3DL3. AA range:231-280 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | KIR3DL3 antibody CD158Z antibody KIR3DL7 antibody KIRC1 antibody Killer cell immunoglobulin-like receptor 3DL3 antibody CD158 antigen-like family member Z antibody Killer cell inhibitory receptor 1 antibody CD158z antibody |
|---|---|
| Molecular Weight(MW) | 45 kDa |
| SwissProt ID | Q8N743 |
|---|
| Positive Control | Peripheral blood, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
