| Product Name | CD177 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD177 antibody; NB1 antibody; PRV1 antibody; CD177 antigen antibody; Human neutrophil alloantigen 2a antibody; HNA-2a antibody; NB1 glycoprotein antibody; NB1 GP antibody; Polycythemia rubra vera protein 1 antibody; PRV-1 antibody; CD177 antibody; |
| Product description | This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human CD177. AA range:361-410 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CD177 antibody NB1 antibody PRV1 antibody CD177 antigen antibody Human neutrophil alloantigen 2a antibody HNA-2a antibody NB1 glycoprotein antibody NB1 GP antibody Polycythemia rubra vera protein 1 antibody PRV-1 antibody CD177 antibody |
|---|---|
| Molecular Weight(MW) | 46 kDa |
| SwissProt ID | Q8N6Q3 |
|---|
| Positive Control | Colon, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
