developmental stage:Its expression is closely related to cellular differentiation in both normal and malignant squamous cells. May act as a protease inhibitor to modulate the host immune response against tumor cells. Belongs to the serpin family. Belongs to the serpin family. Ov-serpin subfamily. subcellular location:Seems to also be secreted in plasma by cancerous cells but at a low level. tissue specificity:Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human SERPINB3/4. AA range:111-160