| Product Name | p57 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CDKN1C antibody; KIP2 antibody; Cyclin-dependent kinase inhibitor 1C antibody; Cyclin-dependent kinase inhibitor p57 antibody; p57Kip2 antibody; |
| Product description | This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human p57Kip2 around the non-acetylation site of Lys278. AA range:241-290 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | CDKN1C antibody KIP2 antibody Cyclin-dependent kinase inhibitor 1C antibody Cyclin-dependent kinase inhibitor p57 antibody p57Kip2 antibody |
|---|---|
| Molecular Weight(MW) | 32 kDa |
| SwissProt ID | P49918 |
|---|
| Positive Control | Embryo,Placenta, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
