HSD17B4 antibody; EDH17B4 antibody; Peroxisomal multifunctional enzyme type 2 antibody; MFE-2 antibody; 17-beta-hydroxysteroid dehydrogenase 4 antibody; 17-beta-HSD 4 antibody; D-bifunctional protein antibody; DBP antibody; Multifunctional protein 2 antibody; MPF-2 antibody;
Product description
The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Immunogen
The antiserum was produced against synthesized peptide derived from the N-terminal region of human HSD17B4. AA range:41-90
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIHC
WB:1:500-1:2000 IHC:1:100-1:300
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
HSD17B4 antibody EDH17B4 antibody Peroxisomal multifunctional enzyme type 2 antibody MFE-2 antibody 17-beta-hydroxysteroid dehydrogenase 4 antibody 17-beta-HSD 4 antibody D-bifunctional protein antibody DBP antibody Multifunctional protein 2 antibody MPF-2 antibody