| Product Name | CD148 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PTPRJ antibody; DEP1 antibody; Receptor-type tyrosine-protein phosphatase eta antibody; Protein-tyrosine phosphatase eta antibody; R-PTP-eta antibody; Density-enhanced phosphatase 1 antibody; DEP-1 antibody; HPTP eta antibody; Protein-tyrosine phosphatase receptor type J antibody; R-PTP-J antibody; CD148 antibody; |
| Product description | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human PTPRJ. AA range:861-910 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | PTPRJ antibody DEP1 antibody Receptor-type tyrosine-protein phosphatase eta antibody Protein-tyrosine phosphatase eta antibody R-PTP-eta antibody Density-enhanced phosphatase 1 antibody DEP-1 antibody HPTP eta antibody Protein-tyrosine phosphatase receptor type J antibody R-PTP-J antibody CD148 antibody |
|---|---|
| Molecular Weight(MW) | 150 kDa |
| SwissProt ID | Q12913 |
|---|
| Positive Control | Colon,Liver,Pancreas,Plasma, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
