| Product Name | FMO3 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FMO3 antibody; Dimethylaniline monooxygenase [N-oxide-forming] 3 antibody; Dimethylaniline oxidase 3 antibody; FMO II antibody; FMO form 2 antibody; Hepatic flavin-containing monooxygenase 3 antibody; FMO 3 antibody; Trimethylamine monooxygenase antibody; |
| Product description | Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. The human FMO gene family is composed of 5 genes and multiple pseudogenes. FMO members have distinct developmental- and tissue-specific expression patterns. The expression of this FMO3 gene, the major FMO expressed in adult liver, can vary up to 20-fold between individuals. This inter-individual variation in FMO3 expression levels is likely to have significant effects on the rate at which xenobiotics are metabolised and, therefore, is of considerable interest to the pharmaceutical industry. This transmembrane protein localizes to the endoplasmic reticulum of many tissues. Alternative splicing of this gen |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human FMO3. AA range:101-150 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | FMO3 antibody Dimethylaniline monooxygenase [N-oxide-forming] 3 antibody Dimethylaniline oxidase 3 antibody FMO II antibody FMO form 2 antibody Hepatic flavin-containing monooxygenase 3 antibody FMO 3 antibody Trimethylamine monooxygenase antibody |
|---|---|
| Molecular Weight(MW) | 58 kDa |
| SwissProt ID | P31513 |
|---|
| Positive Control | Brain,Human lung,Liver,Lung, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
