| Product Name | ZNF384 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ZNF384 antibody; CAGH1 antibody; CIZ antibody; NMP4 antibody; TNRC1 antibody; Zinc finger protein 384 antibody; CAG repeat protein 1 antibody; CAS-interacting zinc finger protein antibody; Nuclear matrix transcription factor 4 antibody; Nuclear matrix protein 4 antibody; Trinucleotide repeat-containing gene 1 protein antibody; |
| Product description | This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. |
| Immunogen | The antiserum was produced against synthesized peptide derived from the N-terminal region of human ZNF384. AA range:1-50 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml |
| Alternative Names | ZNF384 antibody CAGH1 antibody CIZ antibody NMP4 antibody TNRC1 antibody Zinc finger protein 384 antibody CAG repeat protein 1 antibody CAS-interacting zinc finger protein antibody Nuclear matrix transcription factor 4 antibody Nuclear matrix protein 4 antibody Trinucleotide repeat-containing gene 1 protein antibody |
|---|---|
| Molecular Weight(MW) | 64 kDa |
| SwissProt ID | Q8TF68 |
|---|
| Positive Control | Brain,Brain cortex,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
