| Product Name | OAS2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | OAS2 antibody; 2'-5'-oligoadenylate synthase 2 antibody; (2-5')oligo(A) synthase 2 antibody; 2-5A synthase 2 antibody; p69 OAS / p71 OAS antibody; p69OAS / p71OAS antibody; |
| Product description | This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Immunogen | The antiserum was produced against synthesized peptide derived from the N-terminal region of human OAS2. AA range:61-110 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | OAS2 antibody 2'-5'-oligoadenylate synthase 2 antibody (2-5')oligo(A) synthase 2 antibody 2-5A synthase 2 antibody p69 OAS / p71 OAS antibody p69OAS / p71OAS antibody |
|---|---|
| Molecular Weight(MW) | 82 kDa |
| SwissProt ID | P29728 |
|---|
| Positive Control | Blood,Colon,Testis,Uterus, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
