| Product Name | IL-6Rα |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IL6R antibody; Interleukin-6 receptor subunit alpha antibody; IL-6 receptor subunit alpha antibody; IL-6R subunit alpha antibody; IL-6R-alpha antibody; IL-6RA antibody; IL-6R 1 antibody; Membrane glycoprotein 80 antibody; gp80 antibody; CD126 antibody; |
| Product description | This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9., |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human IL6R. AA range:221-270 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| IHC:100-300 WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | IL6R antibody Interleukin-6 receptor subunit alpha antibody IL-6 receptor subunit alpha antibody IL-6R subunit alpha antibody IL-6R-alpha antibody IL-6RA antibody IL-6R 1 antibody Membrane glycoprotein 80 antibody gp80 antibody CD126 antibody |
|---|---|
| Molecular Weight(MW) | 53 kDa |
| SwissProt ID | P08887 |
|---|
| Positive Control | Kidney,Lymph,Pooled, |
|---|---|
| Application Notes | IHC:100-300 WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
