| Product Name | CD89 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FCAR antibody; CD89 antibody; Immunoglobulin alpha Fc receptor antibody; IgA Fc receptor antibody; CD89 antibody; |
| Product description | This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human FCAR. AA range:31-80 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | FCAR antibody CD89 antibody Immunoglobulin alpha Fc receptor antibody IgA Fc receptor antibody CD89 antibody |
|---|---|
| Molecular Weight(MW) | 32 kDa |
| SwissProt ID | P24071 |
|---|
| Positive Control | Alveolar macrophage,Blood,Bone marrow,Monocyte,Pituitary, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
