| Product Name | Talin-1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TLN1 antibody; KIAA1027 antibody; TLN antibody; Talin-1 antibody; |
| Product description | This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. |
| Immunogen | The antiserum was produced against synthesized peptide derived from the C-terminal region of human TLN1. AA range:2471-2520 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | TLN1 antibody KIAA1027 antibody TLN antibody Talin-1 antibody |
|---|---|
| Molecular Weight(MW) | 269 kDa |
| SwissProt ID | Q9Y490 |
|---|
| Positive Control | Aorta,Brain,Embryonic carcinoma,Platelet, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
