| Product Name | LIR-1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LILRB1 antibody; ILT2 antibody; LIR1 antibody; MIR7 antibody; Leukocyte immunoglobulin-like receptor subfamily B member 1 antibody; LIR-1 antibody; Leukocyte immunoglobulin-like receptor 1 antibody; CD85 antigen-like family member J antibody; Immunoglobulin-like transcript 2 antibody; ILT-2 antibody; Monocyte/macrophage immunoglobulin-like receptor 7 antibody; MIR-7 antibody; CD85j antibody; |
| Product description | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. 4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from the N-terminal region of human LILRB1. AA range:21-70 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | LILRB1 antibody ILT2 antibody LIR1 antibody MIR7 antibody Leukocyte immunoglobulin-like receptor subfamily B member 1 antibody LIR-1 antibody Leukocyte immunoglobulin-like receptor 1 antibody CD85 antigen-like family member J antibody Immunoglobulin-like transcript 2 antibody ILT-2 antibody Monocyte/macrophage immunoglobulin-like receptor 7 antibody MIR-7 antibody CD85j antibody |
|---|---|
| Molecular Weight(MW) | 72 kDa |
| SwissProt ID | Q8NHL6 |
|---|
| Positive Control | B-cell,Lymphoblast, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
