| Product Name | IL-12Rβ1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IL12RB1 antibody; IL12R antibody; IL12RB antibody; Interleukin-12 receptor subunit beta-1 antibody; IL-12 receptor subunit beta-1 antibody; IL-12R subunit beta-1 antibody; IL-12R-beta-1 antibody; IL-12RB1 antibody; IL-12 receptor beta component antibody; CD212 antibody; |
| Product description | The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants. |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human IL12RB1. AA range:211-260 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | IL12RB1 antibody IL12R antibody IL12RB antibody Interleukin-12 receptor subunit beta-1 antibody IL-12 receptor subunit beta-1 antibody IL-12R subunit beta-1 antibody IL-12R-beta-1 antibody IL-12RB1 antibody IL-12 receptor beta component antibody CD212 antibody |
|---|---|
| Molecular Weight(MW) | 73 kDa |
| SwissProt ID | P42701 |
|---|
| Positive Control | Colon,Umbilical cord blood, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
