| Product Name | SIRP-α1/β1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SIRPA antibody; BIT antibody; MFR antibody; MYD1 antibody; PTPNS1 antibody; SHPS1 antibody; SIRP antibody; Tyrosine-protein phosphatase non-receptor type substrate 1 antibody; SHP substrate 1 antibody; SHPS-1 antibody; Brain Ig-like molecule with tyrosine-based activation motifs antibody; Bit antibody; CD172 antigen-like family member A antibody; Inhibitory receptor SHPS-1 antibody; Macrophage fusion receptor antibody; MyD-1 antigen antibody; Signal-regulatory protein alpha-1 antibody; Sirp-alpha-1 antibody; Signal-regulatory protein alpha-2 antibody; Sirp-alpha-2 antibody; Signal-regulatory protein alpha-3 antibody; Sirp-alpha-3 antibody; p84 antibody; CD172a antibody; SIRPB1 antibody; Signal-regulatory protein beta-1 isoform 3 antibody; SIRP-beta-1 isoform 3 antibody; |
| Product description | The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternati |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human SIRPA/SIRPB1. AA range:281-330 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SIRPA antibody BIT antibody MFR antibody MYD1 antibody PTPNS1 antibody SHPS1 antibody SIRP antibody Tyrosine-protein phosphatase non-receptor type substrate 1 antibody SHP substrate 1 antibody SHPS-1 antibody Brain Ig-like molecule with tyrosine-based activation motifs antibody Bit antibody CD172 antigen-like family member A antibody Inhibitory receptor SHPS-1 antibody Macrophage fusion receptor antibody MyD-1 antigen antibody Signal-regulatory protein alpha-1 antibody Sirp-alpha-1 antibody Signal-regulatory protein alpha-2 antibody Sirp-alpha-2 antibody Signal-regulatory protein alpha-3 antibody Sirp-alpha-3 antibody p84 antibody CD172a antibody SIRPB1 antibody Signal-regulatory protein beta-1 isoform 3 antibody SIRP-beta-1 isoform 3 antibody |
|---|---|
| Molecular Weight(MW) | 55 kDa |
| Positive Control | Brain,Kidney,Liver,Monocyte,Placenta,Plasma,Skin,Thalamus, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
