| Product Name | CD158e |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KIR3DL1 antibody; CD158E antibody; NKAT3 antibody; NKB1 antibody; Killer cell immunoglobulin-like receptor 3DL1 antibody; CD158 antigen-like family member E antibody; HLA-BW4-specific inhibitory NK cell receptor antibody; MHC class I NK cell receptor antibody; Natural killer-associated transcript 3 antibody; NKAT-3 antibody; p70 natural killer cell receptor clones CL-2/CL-11 antibody; p70 NK receptor CL-2/CL-11 antibody; CD158e antibody; |
| Product description | Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13. 4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the |
| Immunogen | Synthesized peptide derived from Killer cell immunoglobulin-like receptor 3DL1 at AA range: 21-70 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | KIR3DL1 antibody CD158E antibody NKAT3 antibody NKB1 antibody Killer cell immunoglobulin-like receptor 3DL1 antibody CD158 antigen-like family member E antibody HLA-BW4-specific inhibitory NK cell receptor antibody MHC class I NK cell receptor antibody Natural killer-associated transcript 3 antibody NKAT-3 antibody p70 natural killer cell receptor clones CL-2/CL-11 antibody p70 NK receptor CL-2/CL-11 antibody CD158e antibody |
|---|---|
| Molecular Weight(MW) | 50 kDa |
| SwissProt ID | P43629 |
|---|
| Positive Control | Blood,Brain,Lymphoi |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
