| Product Name | K-Ras |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GTPase KRas (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed] antibody; |
| Product description | This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. |
| Immunogen | The antiserum was produced against synthesized peptide derived from the C-terminal region of human KRAS. AA range:150-200 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| IHC:100-300 WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | GTPase KRas (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas N-terminally processed] antibody |
|---|---|
| Molecular Weight(MW) | 22 kDa |
| SwissProt ID | P01116 |
|---|
| Positive Control | Brain,Cervix carcinoma,Colon carcinoma,Gallbladder tumor,Lung,Lung carcinom |
|---|---|
| Application Notes | IHC:100-300 WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
