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EpCAM [SU03-32]

Catalog Number:OM637228
OM637228
Discount Price
OM637228-100ul
1~2 Week
100ul
OM637228-50ul
50ul
OM637228-20ul
20ul
1~2 Week
Product Profile
Product Name EpCAM [SU03-32]
Antibody Type Primary Antibodies
Antigen Alias 17 1A antibody 323/A3 antibody Adenocarcinoma associated antigen antibody Adenocarcinoma-associated antigen antibody Antigen identified by monoclonal antibody AUA1 antibody AUA1 antibody CD326 antibody CD326 antigen antibody Cell surface glycoprotein Trop 1 antibody Cell surface glycoprotein Trop 2 antibody Cell surface glycoprotein Trop-1 antibody CO 17A antibody CO17 1A antibody CO17A antibody DIAR5 antibody EGP 2 antibody EGP antibody EGP2 antibody EGP314 antibody EGP40 antibody Ep CAM antibody Ep-CAM antibody EPCAM antibody EPCAM_HUMAN antibody EpCAM1 antibody Epithelial cell adhesion molecule antibody Epithelial Cell Adhesion Molecule Intracellular Domain (EpCAM-ICD) antibody Epithelial cell surface antigen antibody Epithelial cellular adhesion molecule antibody Epithelial glycoprotein 1 antibody Epithelial glycoprotein 314 antibody Epithelial glycoprotein antibody ESA antibody GA733 1 antibody GA733 2 antibody GA733-2 antibody gastrointestinal tumor-associated antigen 2, 35-KD glycoprotein antibody gp4 antibody hEGP 2 antibody hEGP314 antibody HNPCC8 antibody Human epithelial glycoprotein 2 antibody KS 1/4 antigen antibody KS1/4 antibody KSA antibody Ly74 antibody Lymphocyte antigen 74 antibody M1S 1 antibody M1S2 antibody M4S1 antibody Major gastrointestinal tumor associated protein GA733 2 antibody Major gastrointestinal tumor-associated protein GA733-2 antibody mEGP314 antibody Membrane component chromosome 4 surface marker (35kD glycoprotein) antibody Membrane component, chromosome 4, surface marker 1 antibody Membrane component, chromosome 4, surface marker antibody MIC18 antibody MK 1 antibody Protein 289A antibody TACD1 antibody TACSTD1 antibody TROP1 antibody Tumor associated calcium signal transducer 1 antibody Tumor associated calcium signal transducer 2 precursor antibody Tumor-associated calcium signal transducer 1 antibody
Product description EPCAM is a carcinoma-associated antigen and belongs to a family which includes at least 2 type I membrane proteins. The EPCAM protein has a role in embryonic stem cells proliferation and differentiation. EPCAM is used as a target for immunotherapy treatment of human carcinomas. EPCAM is expressed on most normal epithelial cells and gastrointestinal carcinomas and acts as a homotypic calcium-independent cell adhesion molecule. Epithelial cell adhesion molecules (EPCAM) can act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for supplying immunological barrier as a first line of defense against mucosal infection. EPCAM gene mutations result in congenital tufting enteropathy.
Immunogen recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBIHC
WB:1:1,000-1:2,000
IHC:1:100-1:500
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Target Information
Alternative Names 17 1A antibody 323/A3 antibody Adenocarcinoma associated antigen antibody Adenocarcinoma-associated antigen antibody Antigen identified by monoclonal antibody AUA1 antibody AUA1 antibody CD326 antibody CD326 antigen antibody Cell surface glycoprotein Trop 1 antibody Cell surface glycoprotein Trop 2 antibody Cell surface glycoprotein Trop-1 antibody CO 17A antibody CO17 1A antibody CO17A antibody DIAR5 antibody EGP 2 antibody EGP antibody EGP2 antibody EGP314 antibody EGP40 antibody Ep CAM antibody Ep-CAM antibody EPCAM antibody EPCAM_HUMAN antibody EpCAM1 antibody Epithelial cell adhesion molecule antibody Epithelial Cell Adhesion Molecule Intracellular Domain (EpCAM-ICD) antibody Epithelial cell surface antigen antibody Epithelial cellular adhesion molecule antibody Epithelial glycoprotein 1 antibody Epithelial glycoprotein 314 antibody Epithelial glycoprotein antibody ESA antibody GA733 1 antibody GA733 2 antibody GA733-2 antibody gastrointestinal tumor-associated antigen 2
35-KD glycoprotein antibody gp4 antibody hEGP 2 antibody hEGP314 antibody HNPCC8 antibody Human epithelial glycoprotein 2 antibody KS 1/4 antigen antibody KS1/4 antibody KSA antibody Ly74 antibody Lymphocyte antigen 74 antibody M1S 1 antibody M1S2 antibody M4S1 antibody Major gastrointestinal tumor associated protein GA733 2 antibody Major gastrointestinal tumor-associated protein GA733-2 antibody mEGP314 antibody Membrane component chromosome 4 surface marker (35kD glycoprotein) antibody Membrane component
chromosome 4
surface marker 1 antibody Membrane component
chromosome 4
surface marker antibody MIC18 antibody MK 1 antibody Protein 289A antibody TACD1 antibody TACSTD1 antibody TROP1 antibody Tumor associated calcium signal transducer 1 antibody Tumor associated calcium signal transducer 2 precursor antibody Tumor-associated calcium signal transducer 1 antibody
Molecular Weight(MW) 35 kDa
Cellular Localization Lateral cell membrane, Cell junction.
Database Links
Application

Application

Fig1: Western blot analysis of EpCAM on different lysates using anti-EpCAM antibody at 1/1,000 dilution. Positive control: Lane 1: HCT116 Lane 2: SW480

Application

Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-EpCAM antibody. Counter stained with hematoxylin.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-EpCAM antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-EpCAM antibody. Counter stained with hematoxylin.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-EpCAM antibody. Counter stained with hematoxylin.

Application

Fig6: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-EpCAM antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-EpCAM antibody. Counter stained with hematoxylin.

Application

Fig8: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-EpCAM antibody. Counter stained with hematoxylin.

Application

Fig9: Immunohistochemical analysis of paraffin-embedded mouse stomach tissue using anti-EpCAM antibody. Counter stained with hematoxylin.
Positive Control HCT116, SW480, human tonsil tissue, human liver tissue, human colon tissue, human breast tissue, human colon cancer tissue, human breast carcinoma tissue.
Application Notes WB:1:1,000-1:2,000
IHC:1:100-1:500
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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