Application
Fig1: Western blot analysis of Phospho-GATA3(S308) on human skin lysates using anti-Phospho-GATA3(S308) antibody at 1/1,000 dilution.Application
Fig2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-Phospho-GATA3(S308) antibody. Counter stained with hematoxylin.| Product Name | Phospho-GATA3 (S308) [ST44-09] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GATA 3 antibody GATA binding factor 3 antibody GATA binding protein 3 antibody GATA-binding factor 3 antibody Gata3 antibody GATA3_HUMAN antibody HDR antibody HDRS antibody MGC2346 antibody MGC5199 antibody MGC5445 antibody Trans acting T cell specific transcription factor GATA 3 antibody Trans-acting T-cell-specific transcription factor GATA-3 antibody |
| Product description | GATA-3 antibody (GATA binding protein 3) is a member of the GATA family of transcription factors. GATA-3 appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 has a strong association with estrogen receptor-alpha expression in breast cancer and evidence exists that GATA-3 may be used to predict response to hormonal therapy of breast cancer patients. GATA-3 has also been shown to be a novel marker for bladder cancer. In one study, GATA-3 stained 67% of 308 urothelial carcinomas but no prostate or renal carcinomas. |
| Immunogen | Synthetic phospho-peptide corresponding to residues surrounding Ser308 of human GATA3. |
| Modification | p-S308 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHCIP |
| WB:1:1,000-1:2,000 IHC:1:50-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GATA 3 antibody GATA binding factor 3 antibody GATA binding protein 3 antibody GATA-binding factor 3 antibody Gata3 antibody GATA3_HUMAN antibody HDR antibody HDRS antibody MGC2346 antibody MGC5199 antibody MGC5445 antibody Trans acting T cell specific transcription factor GATA 3 antibody Trans-acting T-cell-specific transcription factor GATA-3 antibody |
|---|---|
| Molecular Weight(MW) | 48 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | P23771 |
|---|
Application
Fig1: Western blot analysis of Phospho-GATA3(S308) on human skin lysates using anti-Phospho-GATA3(S308) antibody at 1/1,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-Phospho-GATA3(S308) antibody. Counter stained with hematoxylin.| Positive Control | Human skin tissue, human breast carcinoma tissue. |
|---|---|
| Application Notes | WB:1:1,000-1:2,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
