Application
Fig1: Western blot analysis of IgG4 on human plasma lysates using anti-IgG4 antibody at 1/1,000 dilution.Application
Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-IgG4 antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-IgG4 antibody. Counter stained with hematoxylin.| Product Name | IgG4 [ST05-12] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Ig gamma 4 chain C region antibody IGHG4 antibody Immunoglobulin heavy constant gamma 4 (G4m marker) antibody MGC117419 antibody |
| Product description | The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Several studies have shown that a large population of patients with recurrent respiratory tract infection have low IgG4 concentrations. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:1,000-1:5,000 IHC:1:50-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Ig gamma 4 chain C region antibody IGHG4 antibody Immunoglobulin heavy constant gamma 4 (G4m marker) antibody MGC117419 antibody |
|---|---|
| Molecular Weight(MW) | 36 kDa |
| Cellular Localization | Secreted. |
| SwissProt ID | P01861 |
|---|
Application
Fig1: Western blot analysis of IgG4 on human plasma lysates using anti-IgG4 antibody at 1/1,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-IgG4 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-IgG4 antibody. Counter stained with hematoxylin.| Positive Control | Human tonsil tissue, human spleen tissue, human plasma tissue. |
|---|---|
| Application Notes | WB:1:1,000-1:5,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
