Application
Fig1: Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-Cytokeratin 9 antibody. Counter stained with hematoxylin.| Product Name | Cytokeratin 9 [SD201-09] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CK 9 antibody CK-9 antibody Cytokeratin 9 antibody Cytokeratin-9 antibody Cytokeratin9 antibody EPPK antibody K1C9_HUMAN antibody K9 antibody Keratin 9 antibody Keratin antibody Keratin type I cytoskeletal 9 antibody Keratin-9 antibody Keratin9 antibody KRT 9 antibody Krt9 antibody Spermatid Perinuclear Ring Manchette Protein K9 antibody type I cytoskeletal 9 antibody |
| Product description | Cytokeratins comprise a diverse group of intermediate filament proteins that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratin 9 is an unusually large, type I acidic cytokeratin that differentiates human plantar and palmar epidermal cells. Cytokeratin 9 localizes to the suprabasal layers as well as the upper epidermal layers such as the glandular ridges and interridges. The domains of cytokeratin 9 include a head, an α-helical coiled-coil-forming rod, and a tail; cytokeratin 9 shares significant homology with cytokeratin 10. Mutations in the cytokeratin 9 gene correlate with the development of epidermolytic palmoplantar keratoderma (EPPK), an autosomal dominant inherited skin disorder that is characterized by hyperkeratosis of the skin over the palms and soles. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHCIP |
| WB:1:500-1:1,000 IHC:1:50-1:200 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | CK 9 antibody CK-9 antibody Cytokeratin 9 antibody Cytokeratin-9 antibody Cytokeratin9 antibody EPPK antibody K1C9_HUMAN antibody K9 antibody Keratin 9 antibody Keratin antibody Keratin type I cytoskeletal 9 antibody Keratin-9 antibody Keratin9 antibody KRT 9 antibody Krt9 antibody Spermatid Perinuclear Ring Manchette Protein K9 antibody type I cytoskeletal 9 antibody |
|---|---|
| Molecular Weight(MW) | 62 kDa |
| Cellular Localization | Extracellular exosome, membrane, nucleus. |
Application
Fig1: Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-Cytokeratin 9 antibody. Counter stained with hematoxylin.| Positive Control | Mouse skin tissue. |
|---|---|
| Application Notes | WB:1:500-1:1,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
