Application
Fig1: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Pax2 antibody. Counter stained with hematoxylin.| Product Name | Pax2 [JJ082-08] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FSGS7 antibody Paired box 2 antibody Paired box gene 2 antibody paired box homeotic gene 2 antibody paired box protein 2 antibody Paired box protein Pax 2 antibody Paired box protein Pax-2 antibody Paired box protein Pax2 antibody PAPRS antibody Pax 2 antibody |
| Product description | Pax genes contain paired domains with strong homology to genes in Drosophila which are involved in programming early development. The PAX2 gene is expressed in primitive cells of the kidney, ureter, eye, ear, and central nervous system. More specifically, in human embryo sections, PAX2 is expressed in the optic vesicle and later in the retina, in the otic vesicle and later in the semicircular canals of the inner ear, and in mesonephros, metanephros, adrenals, spinal cord, and hindbrain. PAX2 mutations can be responsible for renal hypoplasia, either isolated or associated with various ophthalmologic manifestations ranging from retinal coloboma to microphthalmia. Lesions in the PAX6 gene accounts for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. PAX6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:1,000 IHC:1:50-1:100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | FSGS7 antibody Paired box 2 antibody Paired box gene 2 antibody paired box homeotic gene 2 antibody paired box protein 2 antibody Paired box protein Pax 2 antibody Paired box protein Pax-2 antibody Paired box protein Pax2 antibody PAPRS antibody Pax 2 antibody |
|---|---|
| Molecular Weight(MW) | 45 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | Q02962 |
|---|
Application
Fig1: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Pax2 antibody. Counter stained with hematoxylin.| Positive Control | Human kidney tissue. |
|---|---|
| Application Notes | WB:1:1,000 IHC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
