Application
Fig1: Western blot analysis of SIRT5 on Jurkat cells lysates using anti-SIRT5 antibody at 1/1,000 dilution.| Product Name | SIRT5 [JJ084-01] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NAD dependent deacetylase sirtuin 5 antibody NAD dependent lysine demalonylase and desuccinylase sirtuin 5 mitochondrial antibody NAD dependent protein deacylase sirtuin 5 mitochondrial antibody NAD-dependent protein deacylase sirtuin-5, mitochondrial antibody Regulatory protein SIR2 homolog 5 antibody Silent mating type information regulation 2 S.cerevisiae homolog 5 antibody Sir2 like 5 antibody SIR2-like protein 5 antibody SIR2L5 antibody SIR5_HUMAN antibody Sirt5 antibody Sirtuin 5 antibody Sirtuin type 5 antibody |
| Product description | SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WB |
| WB:1:1,000-1:2,000 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | NAD dependent deacetylase sirtuin 5 antibody
NAD dependent lysine demalonylase and desuccinylase sirtuin 5 mitochondrial antibody
NAD dependent protein deacylase sirtuin 5 mitochondrial antibody
NAD-dependent protein deacylase sirtuin-5 mitochondrial antibody Regulatory protein SIR2 homolog 5 antibody Silent mating type information regulation 2 S.cerevisiae homolog 5 antibody Sir2 like 5 antibody SIR2-like protein 5 antibody SIR2L5 antibody SIR5_HUMAN antibody Sirt5 antibody Sirtuin 5 antibody Sirtuin type 5 antibody |
|---|---|
| Molecular Weight(MW) | 37/22 kDa |
| Cellular Localization | Cytoplasm, Nucleus, Mitochondrion. |
Application
Fig1: Western blot analysis of SIRT5 on Jurkat cells lysates using anti-SIRT5 antibody at 1/1,000 dilution.| Positive Control | Jurkat. |
|---|---|
| Application Notes | WB:1:1,000-1:2,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
