Application
Fig1: Western blot analysis of ABL2 on different lysates using anti-ABL2 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela Lane 2: PC-12 Lane 3: JurkatApplication
Fig2: Flow cytometric analysis of Raji cells with ABL2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody| Product Name | ABL2 [JF0951] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Abelson murine leukemia viral oncogene homolog 2 antibody Abelson related gene protein antibody Abelson tyrosine-protein kinase 2 antibody Abelson-related gene protein antibody ABL2 antibody ABL2_HUMAN antibody ABLL antibody ARG antibody Tyrosine kinase ARG antibody Tyrosine protein kinase ABL2 antibody Tyrosine-protein kinase ARG antibody v abl Abelson murine leukemia viral oncogene homolog 2 antibody |
| Product description | The Abl oncogene was initially identified as the viral transforming gene of Abelson murine leukemia virus (A-MuLV). The major translational product of c-Abl has been identified as a protein with tyrosine kinase activity and an SH2 domain. The Abl oncogene is implicated in several human leukemias including chronic myelocytic leukemia (CML), in which it undergoes a (9;22) chromosomal translocation and produces the Philadelphia (Ph1) chromosome. The molecular consequence of this translocation is the generation of a chimeric Bcr/c-Abl mRNA encoding activated Abl protein tyrosine kinase. The related protein tyrosine kinase Arg, also designated Abl2, contains an SH2 and an SH3 domain. Arg has been shown to interact with and to phosphorylate c-Crk. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBFC |
| WB:1:1,000-1:2,000 FC:1:50-1:100 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | Abelson murine leukemia viral oncogene homolog 2 antibody Abelson related gene protein antibody Abelson tyrosine-protein kinase 2 antibody Abelson-related gene protein antibody ABL2 antibody ABL2_HUMAN antibody ABLL antibody ARG antibody Tyrosine kinase ARG antibody Tyrosine protein kinase ABL2 antibody Tyrosine-protein kinase ARG antibody v abl Abelson murine leukemia viral oncogene homolog 2 antibody |
|---|---|
| Molecular Weight(MW) | 128 kDa |
| Cellular Localization | Cytoplasm, cytoskeleton. |
Application
Fig1: Western blot analysis of ABL2 on different lysates using anti-ABL2 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela Lane 2: PC-12 Lane 3: Jurkat
Application
Fig2: Flow cytometric analysis of Raji cells with ABL2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody| Positive Control | PC-12, Jurakt, Hela. |
|---|---|
| Application Notes | WB:1:1,000-1:2,000 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
