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Cathepsin B [JA11-02]

Catalog Number:OM637925
OM637925
Discount Price
OM637925-100ul
1~2 Week
100ul
OM637925-50ul
50ul
OM637925-20ul
20ul
1~2 Week
Product Profile
Product Name Cathepsin B [JA11-02]
Antibody Type Primary Antibodies
Antigen Alias Amyloid precursor protein secretase antibody APP secretase antibody APPS antibody CATB_HUMAN antibody Cathepsin B heavy chain antibody Cathepsin B1 antibody CathepsinB antibody CPSB antibody CTSB antibody cysteine protease antibody OTTHUMP00000116009 antibody OTTHUMP00000229510 antibody OTTHUMP00000229511 antibody OTTHUMP00000229512 antibody OTTHUMP00000229514 antibody OTTHUMP00000229515 antibody OTTHUMP00000229516 antibody Preprocathepsin B antibody
Product description The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin B is expressed in luminal epithelial cells, indicating that cathepsin B is a marker for secretory cell death.
Immunogen recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBICC/IFIHC
WB:1:500-1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names Amyloid precursor protein secretase antibody APP secretase antibody APPS antibody CATB_HUMAN antibody Cathepsin B heavy chain antibody Cathepsin B1 antibody CathepsinB antibody CPSB antibody CTSB antibody cysteine protease antibody OTTHUMP00000116009 antibody OTTHUMP00000229510 antibody OTTHUMP00000229511 antibody OTTHUMP00000229512 antibody OTTHUMP00000229514 antibody OTTHUMP00000229515 antibody OTTHUMP00000229516 antibody Preprocathepsin B antibody
Molecular Weight(MW) 38 kDa
Cellular Localization Lysosome. Melanosome.
Database Links
SwissProt ID P07858
Application

Application

Fig1: Western blot analysis of Cathepsin B on different cells lysates using anti-Cathepsin B antibody at 1/500 dilution. Positive control: Lane 1: HepG2 Lane 2: Hela Lane 3:A549

Application

Fig2: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Cathepsin B antibody. Counter stained with hematoxylin.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Cathepsin B antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-Cathepsin B antibody. Counter stained with hematoxylin.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-Cathepsin B antibody. Counter stained with hematoxylin.

Application

Fig6: Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue using anti-Cathepsin B antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Cathepsin B antibody. Counter stained with hematoxylin.
Positive Control HepG2, A549, Hela, human liver tissue, human liver cancer tissue, human pancreas tissue, mouse pancreas tissue, mouse brain tissue.
Application Notes WB:1:500-1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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