Application
Fig1: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-FAP1 antibody. Counter stained with hematoxylin.| Product Name | FAP1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | APO1/CD95 (Fas) associated phosphatase antibody DKFZp686J1497 antibody FAP 1 antibody FAP1 antibody Fas associated phosphatase 1 antibody Fas associated protein tyrosine phosphatase 1 antibody HGNC:9646 antibody hPTPE1 antibody Phosphatase rip antibody PNP 1 antibody PNP1 antibody Protein tyrosine phosphatase 1 Fas associated antibody protein tyrosine phosphatase 1E antibody Protein tyrosine phosphatase non receptor type 13 antibody Protein tyrosine phosphatase nonreceptor type 13 antibody Protein tyrosine phosphatase PTPL1 antibody protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) antibody PTP BAS antibody PTP BL antibody PTP E1 antibody PTP1E antibody PTPL 1 antibody PTPL1 antibody PTPLE antibody PTPN 13 antibody PTPN13 antibody Tyrosine protein phosphatase non receptor type 13 antibody |
| Product description | FAP (fibroblast activation protein) is a cell surface glycoprotein and serine protease that is expressed primarily in fetal mesenchymal tissues and epithelial cancer fibroblasts. In cancer, FAP functions to promote cellular proliferation. In embryonic development, FAP functions to remodel developing tissues. FAP acts as an integral membrane gelatinase composed of N-glycosylated proteolytically inactive subunits. FAP expression on chondrocyte membranes is upregulated by the combination of the cytokines IL-1 and OSM and has been shown to increase in osteoarthritic patients. This expression is co-localized with MMP-1and MMP-13 as well as CD44 (variants v3 and v7/8). Mice that lack all copies of the FAP gene have been found to be fertile and to have developmental defects or change in cancer susceptibility. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:1,000 IHC:1:50-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | APO1/CD95 (Fas) associated phosphatase antibody
DKFZp686J1497 antibody
FAP 1 antibody
FAP1 antibody
Fas associated phosphatase 1 antibody
Fas associated protein tyrosine phosphatase 1 antibody
HGNC:9646 antibody
hPTPE1 antibody
Phosphatase rip antibody
PNP 1 antibody
PNP1 antibody
Protein tyrosine phosphatase 1 Fas associated antibody
protein tyrosine phosphatase 1E antibody
Protein tyrosine phosphatase non receptor type 13 antibody
Protein tyrosine phosphatase nonreceptor type 13 antibody
Protein tyrosine phosphatase PTPL1 antibody
protein tyrosine phosphatase non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) antibody PTP BAS antibody PTP BL antibody PTP E1 antibody PTP1E antibody PTPL 1 antibody PTPL1 antibody PTPLE antibody PTPN 13 antibody PTPN13 antibody Tyrosine protein phosphatase non receptor type 13 antibody |
|---|---|
| Molecular Weight(MW) | 95 kDa |
| Cellular Localization | Cell membrane. Cell surface. |
| SwissProt ID | Q12884 |
|---|
Application
Fig1: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-FAP1 antibody. Counter stained with hematoxylin.| Positive Control | Human colon cancer tissue. |
|---|---|
| Application Notes | WB:1:500-1:1,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
