Application
Fig1: Western blot analysis of SFRP1 on human kidney cells lysates using anti-SFRP1 antibody at 1/500 dilution.| Product Name | SFRP1 [JA11-68] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Frizzled related protein 1 antibody FRP 1 antibody FRP antibody FRP-1 antibody FRP1 antibody FrzA antibody SARP 2 antibody SARP-2 antibody SARP2 antibody Secreted apoptosis related protein 2 antibody Secreted apoptosis-related protein 2 antibody Secreted frizzled related protein 1 antibody Secreted frizzled related protein antibody Secreted frizzled-related protein 1 antibody SFRP 1 antibody sFRP-1 antibody SFRP1 antibody SFRP1_HUMAN antibody |
| Product description | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WB |
| WB:1:500-1:2,000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Frizzled related protein 1 antibody FRP 1 antibody FRP antibody FRP-1 antibody FRP1 antibody FrzA antibody SARP 2 antibody SARP-2 antibody SARP2 antibody Secreted apoptosis related protein 2 antibody Secreted apoptosis-related protein 2 antibody Secreted frizzled related protein 1 antibody Secreted frizzled related protein antibody Secreted frizzled-related protein 1 antibody SFRP 1 antibody sFRP-1 antibody SFRP1 antibody SFRP1_HUMAN antibody |
|---|---|
| Molecular Weight(MW) | 35 kDa |
| Cellular Localization | Secreted. |
| SwissProt ID | Q8N474 |
|---|
Application
Fig1: Western blot analysis of SFRP1 on human kidney cells lysates using anti-SFRP1 antibody at 1/500 dilution.| Positive Control | Human kidney cells lysates. |
|---|---|
| Application Notes | WB:1:500-1:2,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
