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CD39 Recombinant Rabbit Monoclonal Antibody

Catalog Number:OM637991
OM637991
Discount Price
OM637991-100ul
1~2 Week
100ul
OM637991-50ul
50ul
OM637991-20ul
20ul
1~2 Week
Product Profile
Product Name CD39 Recombinant Rabbit Monoclonal Antibody
Antibody Type Primary Antibodies
Product description

CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENP1), is an integral membrane glycoprotein that acts as an extracellular nucleotide-hydrolyzing enzyme. CD39 inhibits ADP-induced platelet aggregation by hydrolyzing ADP to AMP and ultimately generating adenosine. Intracellular CD39 undergoes glycosylation at 6 N-glycosylation sites and translocates to the membrane in order to be an active enzyme. Alternative splicing gives rise to three CD39 isoforms, vascular, placenta I and placenta II. The placenta I isoform differs at the amino terminus whereas the placenta II isoform is missing amino acids 300-510 at the C-terminus. CD39 is expressed in vascular tissues including placenta, lung, skeletal muscle and kidney, as well as endothelium, smooth muscle, cardiac cells, lymphocytes (such as activated B cells) activated NK cells, macrophages, dendridic cells and platelets. CD39 may be used as an anti-thrombic agent for pre-treating patients at risk for coronary artery occlusion and thrombic stroke.

Immunogen recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications IHCWB
WB:1:500-1:1,000
IHC:1:50-1:200
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Alternative Names ATPDase antibody CD 39 antibody CD39 antibody CD39 antigen antibody DKFZp686D194 antibody DKFZp686I093 antibody Ecto apyrase antibody Ecto ATP diphosphohydrolase antibody Ecto-apyrase antibody Ecto-ATP diphosphohydrolase 1 antibody Ecto-ATPase 1 antibody Ecto-ATPDase 1 antibody Ectonucleoside triphosphate diphosphohydrolase 1 antibody ENTP1_HUMAN antibody ENTPD 1 antibody ENTPD1 antibody FLJ40921 antibody FLJ40959 antibody Lymphoid cell activation antigen antibody NTPDase 1 antibody NTPDase1 antibody SPG64 antibody
Molecular Weight(MW) 70 kDa
Cellular Localization Membrane.
Database Links
Application

Application

Fig1: Western blot analysis of CD39 on different cell lysate using anti-CD39 antibody at 1/1,000 dilution. Positive control: Lane1: Human spleen Lane2: Mouse placenta Lane3: Mouse spleen

Application

Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD39 antibody. Counter stained with hematoxylin.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD39 antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-CD39 antibody. Counter stained with hematoxylin.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded mouse uterus tissue using anti-CD39 antibody. Counter stained with hematoxylin.
Positive Control Human spleen tissue lysate, mouse placenta tissue, mouse spleen tissue, human tonsil tissue, human spleen tissue, human placenta tissue, mouse uterus tissue.
Application Notes WB:1:500-1:1,000
IHC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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