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Protein C [JM93-61]

Catalog Number:OM638034
OM638034
Discount Price
OM638034-100ul
1~2 Week
100ul
OM638034-50ul
50ul
OM638034-20ul
20ul
1~2 Week
Product Profile
Product Name Protein C [JM93-61]
Antibody Type Primary Antibodies
Product description Protein C is a vitamin K-dependent plasma protein that is produced in the liver and made up of two polypeptide chains. It is an important anti-coagulant activated by Thrombin bound to an endothelial surface receptor and it enzymatically cleaves activated forms of Factors V and VIII, dest? inflammatory blood coagulation. Protein C is similar to the prothrombin group of blood coagulation factors in its primary structure. Normal protein C concentration in human plasma is approximately 1-3 ng / ml and the proenzyme concentration is approximately 3 μg / ml. Protein C deficiency is associated with inherited thrombophilia, a rare genetic disorder that predisposes affected individuals to venous thrombosis and habitual abortion.
Immunogen recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBICCIHC
WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
Species Reactivity Human
Concentration 1mg/ml
Target Information
Molecular Weight(MW) 52 kDa
Cellular Localization Endoplasmic reticulum, Secreted.
Database Links
SwissProt ID P04070
Application

Application

Fig1: ICC staining Protein C in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig2: ICC staining Protein C in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Protein C antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Protein C antibody. Counter stained with hematoxylin.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue using anti-Protein C antibody. Counter stained with hematoxylin.
Positive Control 293T, Hela, human liver tissue.
Application Notes WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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