Application
Fig1: Western blot analysis of PI 3 Kinase p110 delta on mouse spleen tissue lysate using anti-PI 3 Kinase p110 delta antibody at 1/1,000 dilution.Application
Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PI 3 Kinase p110 delta antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-PI 3 Kinase p110 delta antibody. Counter stained with hematoxylin.| Product Name | PI 3 Kinase p110 delta [JM83-24] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 5-bisphosphate 3-kinase 110 kDa catalytic subunit delta antibody 5-bisphosphate 3-kinase catalytic subunit delta isoform antibody APDS antibody GRB1 antibody IMD14 antibody p110d antibody p110delta antibody p110dp85a antibody p85-ALPHA antibody Phosphatidylinositol 3 kinase catalytic delta polypeptide antibody Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit delta isoform antibody Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit delta antibody Phosphatidylinositol 4,5 bisphosphate 3 kinase, catalytic subunit delta antibody Phosphatidylinositol 45 bisphosphate 3 kinase catalytic subunit delta isoform antibody Phosphatidylinositol-4 antibody Phosphoinositide 3 kinase B antibody Phosphoinositide 3 kinase C antibody Phosphoinositide 3 kinase catalytic delta polypeptide antibody Phosphoinositide 3 kinase, catalytic, delta polypeptide variant p37delta antibody PI3 kinase p110 subunit delta antibody PI3-kinase subunit delta antibody PI3K antibody PI3K-delta antibody PI3Kdelta antibody Pik3cd antibody PIK3R1 antibody PK3CD antibody PK3CD_HUMAN antibody PtdIns 3 kinase p110 antibody PtdIns 3 kinase subunit p110 delta antibody PtdIns-3-kinase subunit delta antibody PtdIns-3-kinase subunit p110-delta antibody |
| Product description | Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85α and p85β), each possessing one SH3 and two SH2 domains. Various p110 forms have been identified. p110α and p110β interact with p85α, and p110α has also been shown to interact with p85β in vitro. It has been shown to bind p85α and β, but it apparently does not phosphorylate these subunits. p110δ has the capacity to autophosphorylate and results in the nearly complete inactivation of the lipid kinase activity. Interestingly, p110γ does not interact with the p85 subunits and has been shown to be activated by α and βγ heterotrimeric G proteins. Two p110δ isoforms have been identified and are widely expressed. Isoform 1 is expressed predominantly in leukocytes while isoform 2 is expressed in normal thymus, lung and spleen tissues. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:500 IHC:1:50-1:200 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | 5-bisphosphate 3-kinase 110 kDa catalytic subunit delta antibody
5-bisphosphate 3-kinase catalytic subunit delta isoform antibody
APDS antibody
GRB1 antibody
IMD14 antibody
p110d antibody
p110delta antibody
p110dp85a antibody
p85-ALPHA antibody
Phosphatidylinositol 3 kinase catalytic delta polypeptide antibody
Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit delta isoform antibody
Phosphatidylinositol 4 5 bisphosphate 3 kinase 110 kDa catalytic subunit delta antibody Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit delta antibody Phosphatidylinositol 45 bisphosphate 3 kinase catalytic subunit delta isoform antibody Phosphatidylinositol-4 antibody Phosphoinositide 3 kinase B antibody Phosphoinositide 3 kinase C antibody Phosphoinositide 3 kinase catalytic delta polypeptide antibody Phosphoinositide 3 kinase catalytic delta polypeptide variant p37delta antibody PI3 kinase p110 subunit delta antibody PI3-kinase subunit delta antibody PI3K antibody PI3K-delta antibody PI3Kdelta antibody Pik3cd antibody PIK3R1 antibody PK3CD antibody PK3CD_HUMAN antibody PtdIns 3 kinase p110 antibody PtdIns 3 kinase subunit p110 delta antibody PtdIns-3-kinase subunit delta antibody PtdIns-3-kinase subunit p110-delta antibody |
|---|---|
| Molecular Weight(MW) | 110 kDa |
| Cellular Localization | Cytoplasm. |
Application
Fig1: Western blot analysis of PI 3 Kinase p110 delta on mouse spleen tissue lysate using anti-PI 3 Kinase p110 delta antibody at 1/1,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PI 3 Kinase p110 delta antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-PI 3 Kinase p110 delta antibody. Counter stained with hematoxylin.| Positive Control | Mouse spleen tissue lysate, human tonsil tissue, human spleen tissue. |
|---|---|
| Application Notes | WB:1:500 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
